When depression keeps coming back or does not improve with traditional treatment, it can be hard not to wonder, What else can I try? That question is one reason newer approaches to depression care have become an important part of the conversation. Spravato treatment in Washington DC offers another option for some adults with treatment-resistant depression, using esketamine in a supervised clinical setting.
Spravato is not simply another antidepressant to add to the list. It works differently from many traditional depression medications and is delivered as a nasal spray under the supervision of a healthcare provider. It is currently a treatment option for adults with treatment-resistant depression, with or without an oral antidepressant.
What Does Spravato Treat?
Spravato is primarily used for treatment-resistant depression, meaning depression that has not responded adequately to other treatments. It is also FDA-approved, in combination with an oral antidepressant, for depressive symptoms in adults with major depressive disorder who have acute suicidal thoughts or behavior.
That does not mean Spravato is right for everyone. It should not replace other forms of mental health care. Instead, it gives certain patients another treatment option when conventional approaches have not provided enough relief.
How Does Spravato Help Depression?
Spravato contains esketamine, which works on the brain’s NMDA receptors rather than following the same pathway as many commonly prescribed antidepressants. For someone who has spent months or years trying different treatments, having an option that works differently can be meaningful.
Treatment also looks different from simply picking up a prescription. Spravato is administered in a certified healthcare setting. Patients are monitored for at least two hours afterward because of potential effects including sedation and dissociation.
A Different Option When Depression Hasn’t Let Up
If standard depression treatments have not gotten you where you hoped they would, you have not run out of options. Spravato treatment in Washington DC may offer a different path worth discussing with a qualified mental health professional. Your care team can explain what to expect, answer questions, and help determine whether this approach makes sense for you.
Explore Spravato Treatment with Inspire Behavioral Health
At Inspire Behavioral Health, our licensed clinicians provide compassionate, evidence-based care. For patients considering Spravato, we can help you explore whether this treatment approach may be appropriate for your depression and what to expect from care. We are ready to help you better understand your mental health and feel supported every step of the way. We take time to listen, answer your questions, and create a personalized plan tailored to your needs. If you are ready to gain clarity, find relief, or simply explore your options, we are here to help.
Call Inspire Behavioral Health at 703-592-4600 to schedule a confidential consultation. Let’s discuss how Spravato can help with your treatment-resistant depression.

